1415609-85-6

Basic information

• Product Name: (1R,3R,5R)-1,7-bis(4-hydroxyphenyl)-1,5-epoxy-3-hydroxyheptane
• Synonyms: (1R,3R,5R)-1,7-bis(4-hydroxyphenyl)-1,5-epoxy-3-hydroxyheptane
• CAS NO: 1415609-85-6
• Molecular Weight: 314.381
• Mol File: 1415609-85-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,3R,5R)-1,7-bis(4-hydroxyphenyl)-1,5-epoxy-3-hydroxyheptane(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R,5R)-1,7-bis(4-hydroxyphenyl)-1,5-epoxy-3-hydroxyheptane(1415609-85-6)
• EPA Substance Registry System: (1R,3R,5R)-1,7-bis(4-hydroxyphenyl)-1,5-epoxy-3-hydroxyheptane(1415609-85-6)

Safety Data

• Hazardous Substances Data: 1415609-85-6(Hazardous Substances Data)

Upstream product

• 1415609-87-8 (2R,4S,6R)-2-(4-hydroxyphenethyl)-6-(4-hydroxyphenyl)tetrahydro-2H-pyran-4-ol 
• 878-00-2 4-formylphenyl acetate 
• 91143-05-4 4-(3-oxopropyl)phenyl acetate 
• 107866-55-7 4-(3-hydroxypropyl)phenyl acetate 
• 10210-17-0 3-(4-hydroxyphenyl)propan-1-ol 
• 23795-02-0 3-(4-hydroxy-phenyl)-propionic acid ethyl ester 

Relevant articles and documents

Synthesis of tetrahydropyranyl diarylheptanoids from Dioscorea villosa

Concise syntheses of four tetrahydropyranyl diarylheptanoids isolated from Dioscorea villosa have been described. The key features include Prins cyclization to construct the tetrahydropyran cores, Keck asymmetric allylation, and Mitsunobu inversion. Optimization of the Prins cyclization conditions in order to minimize racemization has been described. Our syntheses also confirmed the absolute stereochemistry of the natural products.