1415831-64-9Relevant articles and documents
Enantioselective addition of diethylzinc to aldehydes catalyzed by (S)-1-alkyl-2-(arylamino)methylpyrrolidine
Hosoda, Naoya,Ito, Hiroki,Takimoto, Tatsuya,Asami, Masatoshi
, p. 1014 - 1022 (2012/11/07)
Several chiral diamines, (S)-1-alkyl-2-(arylamino)methylpyrrolidine, were used as chiral catalysts for the enantioselective addition of diethylzinc to aldehydes. The best results were obtained by employing 0.15 equiv of (S)-2-anilinomethyl-1-benzylpyrrolidine, and chiral secondary alcohols were obtained with high enantiomeric excesses (up to 94% ee).