1415901-76-6

Basic information

• Product Name: C₄₀H₄₇N₉O₅
• CAS NO: 1415901-76-6
• Molecular Weight: 733.87
• Mol File: 1415901-76-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₀H₄₇N₉O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₀H₄₇N₉O₅(1415901-76-6)
• EPA Substance Registry System: C₄₀H₄₇N₉O₅(1415901-76-6)

Safety Data

• Hazardous Substances Data: 1415901-76-6(Hazardous Substances Data)

Upstream product

• 1415506-19-2 3-({2-[(4-{amino-[(E)-hexyloxycarbonylimino]methyl}-phenylamino)methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}pyridin-2-yl-amino)propionic acid 
• 75907-74-3 2-Pyrazinemethanol,3,5,6-trimethyl 
• 211915-06-9 dabigatran etexilate 
• 6092-54-2 n-hexyl chloroformate 

Relevant articles and documents

Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activity

A novel series of prodrugs consisting of dabigatran and 2-hydroxymethyl-3,5,6-trimethylpyrazine (HTMP) were synthesized. The pharmacological results show that all of them possess the effect of anti-platelet aggregation induced by thrombin in vitro. Moreover, one of those compounds, Y-2 (ED50 = 2.1 ± 1.3 mg/kg) shows more potent activity for inhibiting thrombosis in vivo than that of dabigatran etexilate (ED50 = 4.4 ± 2.2 mg/kg).