1415920-00-1

Basic information

• Product Name: Ethyl 4-amino-3,5-difluorobenzoate
• Synonyms: Ethyl 4-amino-3,5-difluorobenzoate
• CAS NO: 1415920-00-1
• Molecular Weight: 201.173
• Mol File: 1415920-00-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethyl 4-amino-3,5-difluorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-amino-3,5-difluorobenzoate(1415920-00-1)
• EPA Substance Registry System: Ethyl 4-amino-3,5-difluorobenzoate(1415920-00-1)

Safety Data

• Hazardous Substances Data: 1415920-00-1(Hazardous Substances Data)

Usage

General Description

Ethyl 4-amino-3,5-difluorobenzoate is a chemical compound with the molecular formula C9H10F2N2O2. It is a derivative of benzoic acid and contains a benzene ring with amino and carboxylic acid functional groups. The compound is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical intermediates. It has also been studied for its potential antifungal and antibacterial properties. Ethyl 4-amino-3,5-difluorobenzoate is a white to off-white crystalline solid with a molecular weight of 216.18 g/mol. Its specific properties and applications make it an important compound for chemical and pharmaceutical research and development.

Upstream product

• 500577-99-1 4‐amino-3,5-difluorobenzoic acid 
• 110301-23-0 4-amino-3,5-difluorobenzonitrile 
• 67567-26-4 4-bromo-2,6-difluoroaniline 
• 5509-65-9 2,6-difluoroaniline 
• 64-17-5 ethanol 

Downstream Products

• 1415919-94-6 (E)-diethyl 4,4′-(2,2′,6,6′-tetrafluoro)azobenzenedicarboxylate 
• 1562995-70-3 ethyl 4-bromo-3,5-difluorobenzoate 
• 1562995-71-4 ethyl 3,5-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 1562995-76-9 ethyl 4-(1-(2-chloro-6-cyclobutylbenzoyl)-1H-pyrazolo[4,3-b]pyridin-3-yl)-3,5-difluorobenzoate 
• 1562995-30-5 4-(1-(2-chloro-6-cyclobutylbenzoyl)-1H-pyrazolo[4,3-b]pyridin-3-yl)-3,5-difluorobenzoic acid 
• 135564-22-6 4-bromo-3,5-difluorobenzaldehyde 
• 1415919-99-1 diethyl (Z)-4,4'-(2,2',6,6'-tetrafluoro)azobenzenedicarboxylate 

Relevant articles and documents

Active ester functionalized azobenzenes as versatile building blocks

Azobenzenes are important molecular switches that can still be difficult to functionalize selectively. A high yielding Pd-catalyzed cross-coupling method under mild conditions for the introduction of NHS esters to azobenzenes and diazocines has been established. Yields were consistently high with very few exceptions. The NHS functionalized azobenzenes react with primary amines quantitatively. These amines are ubiquitous in biological systems and in material science.

Bromofluoro polysubstituted benzaldehyde derivative and preparation method

The invention relates to a bromofluoro polysubstituted benzaldehyde derivative and a preparation method. The preparation method comprises the following steps: obtaining 2,6-difluoro-4-cyano phenylamine under nitrogen protection by using 2,6-difluoro-4-bro

O -fluoroazobenzenes as readily synthesized photoswitches offering nearly quantitative two-way isomerization with visible light

Azobenzene functionalized with ortho-fluorine atoms has a lower energy of the n-orbital of the Z-isomer, resulting in a separation of the E and Z isomers' n→π* absorption bands. Introducing para-substituents allows for further tuning of the absorption spe