1416134-58-1

Basic information

• Product Name: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate
• Synonyms: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate
• CAS NO: 1416134-58-1
• Molecular Weight: 349.448
• Mol File: 1416134-58-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate(1416134-58-1)
• EPA Substance Registry System: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate(1416134-58-1)

Safety Data

• Hazardous Substances Data: 1416134-58-1(Hazardous Substances Data)

Upstream product

• 67-68-5 dimethyl sulfoxide 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 1774-47-6 trimethylsulfoxonium iodide 

Downstream Products

• 1416134-59-2 C₂₀H₂₉ClN₂O₅ 
• 1192500-31-4 (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicylco[3.2.1]octan-6-yl hydrogensulfate 
• 1192651-49-2 (1R,2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide 
• 1192491-61-4 (2S,5R)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide 7-oxo-6-(sulfoxy)monosodium salt 
• 1416134-49-0 (2S,5R)-5-(benzyloxyamino)-piperidine-2-carboxylic acid amide 
• 1192651-80-1 ({[(2S,5R)-2-carbamoyl-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3,2,1]-oct-6-yl]oxy}sulfonyl)tetrabutylammonium salt 
• 1416134-48-9 ethyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate oxalic acid salt 
• 1416134-60-5 5-benzyloxyiminopiperidine-2S-carboxylic acid ethyl ester 
• 1416134-63-8 (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octan-2-carboxylic acid ethyl ester 
• 1463501-46-3 (2S,5S)-1-(tert-butyl) 2-ethyl 5-((benzyloxy)amino)piperidine-1,2-dicarboxylate 
• 1416134-47-8 C₁₅H₂₂N₂O₃ 
• 1487347-86-3 (2S,5S)-N-tert-butoxycarbonyl-5-hydroxy-2-carboxylic acid piperidine 

Relevant articles and documents

Synthesis method of ethyl (2S, 5R)-5-[(benzyloxy)amino]-piperidine-2-carboxylate

The invention discloses a synthesis method of ethyl (2S, 5R)-5-[(benzyloxy)amino]-piperidine-2-carboxylate. The method comprises the following steps: Boc-L-pyroglutamic acid ethyl ester used as an initial raw material and trimethylsulfoxonium iodide under

B-LACTAMASE INHIBITOR AND APPLICATION THEREOF

The present invention relates to a compound of Formula (I)-(IV) useful as β-lactamase inhibitor, a pharmaceutically acceptable salt, ester, solvate or stereoisomer thereof, wherein R1, R2, M and ring A have definitions as those in the specification. The present invention further relates to methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and uses of these compounds. For example, the compounds of the present invention can be used as β-lactamase inhibitors, for treatment and/or prophylaxis of diseases caused by bacterial infections, solving drug-resistance problems caused by β-lactamases, especially bacterial drug-resistant diseases caused by type B metallo-β-lactamases.

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This disclosure provides compositions containing solid forms of sodium (2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate, and methods of manufacturing and using these compositions.