141697-43-0

Basic information

• Product Name: Ethanone, 1-[3-[(trimethylsilyl)ethynyl]phenyl]-
• CAS NO: 141697-43-0
• Molecular Formula: C13H16OSi
• Molecular Weight: 216.355
• Mol File: 141697-43-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[3-[(trimethylsilyl)ethynyl]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[3-[(trimethylsilyl)ethynyl]phenyl]-(141697-43-0)
• EPA Substance Registry System: Ethanone, 1-[3-[(trimethylsilyl)ethynyl]phenyl]-(141697-43-0)

Safety Data

• Hazardous Substances Data: 141697-43-0(Hazardous Substances Data)

Upstream product

• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 139697-98-6 1-(3-ethynylphenyl) ethan-1-one 
• 6136-68-1 3-acethylbenzonitrile 

Relevant articles and documents

Preparation of Solid Polyfunctional Alkynylzinc Pivalates with Enhanced Air and Moisture Stability for Organic Synthesis

We report the preparation of solid and air-stable polyfunctionalized alkynylzinc pivalates from the corresponding alkynes using TMPZnOPiv (TMP=2,2,6,6-tetramethylpiperidyl) as base. These organozinc pivalates are obtained as powders under mild conditions

Cobalt(II)-based Metalloradical Activation of 2-(Diazomethyl)pyridines for Radical Transannulation and Cyclopropanation

A new catalytic method for the denitrogenative transannulation/cyclopropanation of in-situ-generated 2-(diazomethyl)pyridines is described using a cobalt-catalyzed radical-activation mechanism. The method takes advantage of the inherent properties of a CoIII-carbene radical intermediate and is the first report of denitrogenative transannulation/cyclopropanation by a radical-activation mechanism, which is supported by various control experiments. The synthetic benefits of the metalloradical approach are showcased with a short total synthesis of (±)-monomorine.

Aryl Nitriles from Alkynes Using tert -Butyl Nitrite: Metal-Free Approach to C≡C Bond Cleavage

Alkyne C≡C bond breaking, outside of alkyne metathesis, remains an underdeveloped area in reaction discovery. Recently, nitrogenation has been reported to allow nitrile formation from alkynes. A new protocol for the metal-free C≡C bond cleavage of terminal alkynes to produce nitriles is reported. This method provides an opportunity to synthesize a vast range of nitriles containing aryl, heteroaryl, and natural product derivatives (38 examples). In addition, the potential of tBuONO to act as a powerful nitrogenating agent for terminal aryl alkynes is demonstrated. (Figure Presented).