1416985-90-4

Basic information

• Product Name: C₁₇H₁₄N₂O₂
• Synonyms: C₁₇H₁₄N₂O₂
• CAS NO: 1416985-90-4
• Molecular Weight: 278.31
• Mol File: 1416985-90-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₄N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₄N₂O₂(1416985-90-4)
• EPA Substance Registry System: C₁₇H₁₄N₂O₂(1416985-90-4)

Safety Data

• Hazardous Substances Data: 1416985-90-4(Hazardous Substances Data)

Upstream product

• 73568-27-1 2-chloro-6-methylquinoline-3-carbaldehyde 
• 101382-53-0 6-methyl-2-oxo-1,2-dihydroquinoline-3-carbaldehyde 
• 95-55-6 2-amino-phenol 
• 103-89-9 4-Methylacetanilide 

Relevant articles and documents

Synthesis and antitumor activities of some 2-oxo-quinoline-3-Schiff base derivatives

A series of 2-oxo-quinoline-3-Schiff-base derivatives (4a1-4n2) have been designed and synthesized as new antitumor agents. in vitro Antitumor activities were evaluated against four cancer cell lines including MGC80-3, BEL-7404, A549 and NCI-H460. Compounds 4a1, 4a2, 4c2, 4d1, 4d2 and 4l2 exhibited better inhibition activities than commercial antitumor drug 5-fluorouracil (5-fluorouracil, IC50 = 44 ±0.54 μM) on NCI-H460, with IC50 of 35.52 ± 0.86, 16.22 ± 0.71, 11.62 ± 0.52, 5.16 ± 0.37, 7.62 ± 0.46 and 7.66 ± 0.65 μM, respectively.