1417447-19-8

Basic information

• Product Name: 4-(5-(4-(2-(dimethylamino)ethoxy)phenyl)-4-phenyl-1H-imidazol-2-yl)phenol
• CAS NO: 1417447-19-8
• Molecular Weight: 399.492
• Mol File: 1417447-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(5-(4-(2-(dimethylamino)ethoxy)phenyl)-4-phenyl-1H-imidazol-2-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-(4-(2-(dimethylamino)ethoxy)phenyl)-4-phenyl-1H-imidazol-2-yl)phenol(1417447-19-8)
• EPA Substance Registry System: 4-(5-(4-(2-(dimethylamino)ethoxy)phenyl)-4-phenyl-1H-imidazol-2-yl)phenol(1417447-19-8)

Safety Data

• Hazardous Substances Data: 1417447-19-8(Hazardous Substances Data)

Upstream product

• 38469-73-7 1-(4-hydroxyphenyl)-2-phenylethan-1,2-dione 
• 2491-32-9 1-(4-Hydroxyphenyl)-2-phenylethanone 
• 1417447-27-8 1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylethan-1,2-dione 
• 123-08-0 4-hydroxy-benzaldehyde 
• 103-82-2 phenylacetic acid 
• 108-95-2 phenol 

Relevant articles and documents

Design, synthesis, and cytotoxic activities of new 2,4,5-triarylimidazoles

A new group of 2,4,5-triarylimidazoles containing N,N-dimethylaminoethoxy or piperidinyl ethoxy group at the para position of the C-5 phenyl ring were synthesized and their cytotoxic activities were evaluated on three different breast cancer cell lines using MTT assay. The compounds contain various substituents at the para position of C-2 phenyl ring. Among the synthesized compounds, 4-(5-(4-(2-piperidin-1-yl)ethoxy)phenyl)-4-phenyl-1H-imidazol-2-yl) phenol (11e) and 1-2-(4-(2,4-diphenyl-1H-imidazol-5-yl)phenoxy)ethyl) piperidine (11h) with IC50s of less than 0.1 μM on all three cell lines were the most potent cytotoxic compounds.