1417728-45-0

Basic information

• Product Name: 6-methoxy-2,3-diphenylquinazolin-4(3H)-one
• Synonyms: 6-methoxy-2,3-diphenylquinazolin-4(3H)-one
• CAS NO: 1417728-45-0
• Molecular Weight: 328.37
• Mol File: 1417728-45-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-methoxy-2,3-diphenylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-2,3-diphenylquinazolin-4(3H)-one(1417728-45-0)
• EPA Substance Registry System: 6-methoxy-2,3-diphenylquinazolin-4(3H)-one(1417728-45-0)

Safety Data

• Hazardous Substances Data: 1417728-45-0(Hazardous Substances Data)

Upstream product

• 35450-36-3 methyl 2-bromo-5-methoxybenzoate 
• 1527-91-9 N-phenylbenzamidine 
• 1219629-94-3 5-methoxy-2-nitro-N-phenylbenzamide 
• 100-51-6 benzyl alcohol 
• 1377927-08-6 5-methoxy-2-iodo-N-phenylbenzamide 
• 100-46-9 benzylamine 
• 35673-25-7 6-methoxy-2-phenyl-4H-benzo[d][1,3]oxazin-4-one 
• 62-53-3 aniline 
• 147779-39-3 2-benzoylamino-5-methoxy-benzoic acid 
• 98-88-4 benzoyl chloride 
• 6705-03-9 2-Amino-5-methoxybenzoic acid 

Relevant articles and documents

From Methaqualone and Beyond: Structure - Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA

Methaqualone (2-methyl-3-(o-tolyl)-quinazolin-4(3H)-one, MTQ) is a moderately potent positive allosteric modulator (PAM) of GABAA receptors (GABAARs). In a previous structure-activity relationship (SAR) study probing the importance of 2- and 3-substituent

Iron-catalyzed one-pot 2,3-diarylquinazolinone formation from 2-nitrobenzamides and alcohols

A novel approach for the synthesis of 2,3-diarylquinazolinones using iron as catalyst is described. Various 2-nitro-N-arylbenzamides reacted with benzylic alcohols to selectively give the corresponding products in the absence of external oxidant or reduct