14178-15-5 Usage
General Description
2-Phenoxynicotinonitrile is a chemical compound with the molecular formula C12H8N2O. It is a white powder that is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 2-Phenoxynicotinonitrile is mainly used in the production of nicotinonitrile pesticides, which are widely used for the control of insects and pests in agriculture. Additionally, it is also used as a building block in the synthesis of various pharmaceutical compounds. The compound has low solubility in water and is stable under normal conditions, making it suitable for industrial applications. However, it is important to handle this chemical with care as it can be harmful if ingested or inhaled and may cause irritation to the skin and eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 14178-15-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,7 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14178-15:
(7*1)+(6*4)+(5*1)+(4*7)+(3*8)+(2*1)+(1*5)=95
95 % 10 = 5
So 14178-15-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H8N2O/c13-9-10-5-4-8-14-12(10)15-11-6-2-1-3-7-11/h1-8H
14178-15-5Relevant articles and documents
Method for preparing diarylether compound based on CO2 participated C-F bond activation
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Paragraph 0012-0015, (2021/01/04)
The invention discloses a method for preparing a diarylether compound based on CO2 participated C-F bond activation, which comprises the following steps: adding an acetonitrile solution of a 2-fluoropyridine compound into a reaction container, sequentially adding a catalyst palladium acetate Pd(OAc)2, alkali cesium carbonate and phenylsilane PhSiH3, and replacing with CO2 gas for three times, andreacting for 24 hours under the conditions that the CO2 pressure is 1atm and the temperature is 25 DEG C, adding an ice-water mixture after the reaction is finished, performing extraction reaction, dichloromethane extraction, organic phase merging and drying, reduced pressure distillation and silica gel column chromatography to obtain a target product, namely the white solid diarylether compound.Compared with the prior art, the method has the advantages of mild reaction temperature, good selectivity, high yield, easiness in industrialization and the like.
