1417848-71-5

Basic information

• Product Name: C₁₅H₁₂ClF₃N₄O₃
• Synonyms: C₁₅H₁₂ClF₃N₄O₃
• CAS NO: 1417848-71-5
• Molecular Weight: 388.733
• Mol File: 1417848-71-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₂ClF₃N₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₂ClF₃N₄O₃(1417848-71-5)
• EPA Substance Registry System: C₁₅H₁₂ClF₃N₄O₃(1417848-71-5)

Safety Data

• Hazardous Substances Data: 1417848-71-5(Hazardous Substances Data)

Upstream product

• 1014-81-9 3-(trifluoromethoxy)benzoic acid 
• 677713-01-8 ethyl 3-(trifluoromethoxy)benzoate 
• 321195-88-4 3-(trifluoromethoxy)benzohydrazide 
• 1417848-60-2 3,4,6-trichloropyridazine 

Downstream Products

• 1417848-73-7 C₁₅H₁₀ClF₃N₄O₂ 

Relevant articles and documents

TRICYCLIC COMPOUNDS FOR USE AS KINASE INHIBITORS

There is provided compounds of formula (I), wherein R1, R2, X, R3 and R4 have meanings given in the description (and which compounds are optionally substituted as indicated in the description), and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PIM family kinase, such as PIM-1, PIM-2 and/or PIM-3) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease. There is also provided combinations comprising the compounds of formula (I).