1418150-40-9Relevant articles and documents
Synthesis and phytotoxic activity of 1,2,3-triazole derivatives
Borgati, Thiago F.,Alves, Rosemeire B.,Teixeira, Ro?bson R.,De Freitas, Rossimiriam P.,Perdiga?o, Thays G.,Da Silva, Silma F.,Dos Santos, Aline Aparecida,De Jesu?s O. Bastidas, Alberto
, p. 953 - 961 (2013)
Thirteen triazole derivatives bearing halogenated benzyl substituents were synthesized using the Cu-catalyzed azide-alkyne cycloaddition (CuAAC),a leading example of the click chemistry approach,as the key step. The biological activity of the compounds was evaluated,and it was found that these compounds interfere with the germination and radicle growth (shoots and roots) of two dicotyledonous species,Lactuca sativa and Cucumis sativus,and one monocotyledonous species,Allium cepa. The compounds showed predominantly inhibitory activity related to the evaluated species mainly at the concentration of 10-4 mol L-1. Some of them presented inhibitory activity comparable to 2,4-D (2,4-dichlorophenoxyacetic acid),used as positive control.
