1418290-32-0

Basic information

• Product Name: 2-(2-(2-(2-(dimethylamino)benzamido)-N-(4-fluorobenzyl)acetamido)-3-methylbutanamido)benzoic acid
• Synonyms: 2-(2-(2-(2-(dimethylamino)benzamido)-N-(4-fluorobenzyl)acetamido)-3-methylbutanamido)benzoic acid
• CAS NO: 1418290-32-0
• Molecular Weight: 548.614
• Mol File: 1418290-32-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-(2-(2-(dimethylamino)benzamido)-N-(4-fluorobenzyl)acetamido)-3-methylbutanamido)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(2-(2-(dimethylamino)benzamido)-N-(4-fluorobenzyl)acetamido)-3-methylbutanamido)benzoic acid(1418290-32-0)
• EPA Substance Registry System: 2-(2-(2-(2-(dimethylamino)benzamido)-N-(4-fluorobenzyl)acetamido)-3-methylbutanamido)benzoic acid(1418290-32-0)

Safety Data

• Hazardous Substances Data: 1418290-32-0(Hazardous Substances Data)

Upstream product

• 134-20-3 2-carbomethoxyaniline 
• 41270-80-8 N-formylanthranilic acid methyl ester 
• 610-16-2 N,N-dimethylanthranilic acid 
• 748092-23-1 2-(2-(dimethylamino)benzamido)acetic acid 
• 66715-31-9 o-methoxycarbonylphenylisonitrile 
• 1418290-35-3 2-(dimethylamino)-N-(2-oxo-2-(1H-pyrrol-1-yl)ethyl)benzamide 
• 1418290-27-3 methyl 2-(2-(2-(2-(dimethylamino)benzamido)-N-(4-fluorobenzyl)acetamido)-3-methylbutanamido)benzoate 

Relevant articles and documents

The multicomponent approach to N-methyl peptides: Total synthesis of antibacterial (-)-viridic acid and analogues

Two syntheses of natural viridic acid, an unusual triply N-methylated peptide with two anthranilate units, are presented. The first one is based on peptide-coupling strategies and affords the optically active natural product in 20% overall yield over six steps. A more economical approach with only four steps leads to the similarly active racemate by utilizing a Ugi four-component reaction (Ugi-4CR) as the key transformation. A small library of viridic acid analogues is readily available to provide first SAR insight. The biological activities of the natural product and its derivatives against the Gram-negative bacterium Aliivibrio fischeri were evaluated.