141895-41-2

Basic information

• Product Name: (1S,2S,5S,9S)-5-(3,4-Dimethoxy-benzyl)-2,10,10-trimethyl-3-oxa-6-aza-tricyclo[7.1.1.0^2,7]undec-6-en-4-one
• Synonyms: (1S,2S,5S,9S)-5-(3,4-Dimethoxy-benzyl)-2,10,10-trimethyl-3-oxa-6-aza-tricyclo[7.1.1.0^2,7]undec-6-en-4-one
• CAS NO: 141895-41-2
• Molecular Weight: 357.45
• Mol File: 141895-41-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2S,5S,9S)-5-(3,4-Dimethoxy-benzyl)-2,10,10-trimethyl-3-oxa-6-aza-tricyclo[7.1.1.0^2,7]undec-6-en-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S,5S,9S)-5-(3,4-Dimethoxy-benzyl)-2,10,10-trimethyl-3-oxa-6-aza-tricyclo[7.1.1.0^2,7]undec-6-en-4-one(141895-41-2)
• EPA Substance Registry System: (1S,2S,5S,9S)-5-(3,4-Dimethoxy-benzyl)-2,10,10-trimethyl-3-oxa-6-aza-tricyclo[7.1.1.0^2,7]undec-6-en-4-one(141895-41-2)

Safety Data

• Hazardous Substances Data: 141895-41-2(Hazardous Substances Data)

Upstream product

• 120239-95-4 3,5,6,7,8,8a-hexahydro-7,7,8a-trimethyl-<6S-(6α,8α,8αβ)>-6,8-methano-2H-1,4-benzoxazin-2-one 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 141895-37-6 (1S,2S,9S)-5-[1-(3,4-Dimethoxy-phenyl)-meth-(Z)-ylidene]-2,10,10-trimethyl-3-oxa-6-aza-tricyclo[7.1.1.0^2,7]undec-6-en-4-one 

Downstream Products

• 32161-30-1 (S)-3,4-dimethoxyphenylalanine 

Relevant articles and documents

Efficient asymmetric synthesis of amino acids through hydrogenation of the didehydroamino acid residue in cyclic imino-ester derivatives

The trisubstituted olefinic bond of chiral cyclic α,β-didehydroamino acid derivatives was hydrogenated in the presence of Pd/C with >95% diastereoface discrimination to give, after hydrolysis, the corresponding S-amino acids. The reduction of the double bond with L-selectride does not change the orientation of diastereoface discrimination and the diastereoselectivity is still high.