141975-09-9Relevant articles and documents
Antitumor agents. V. Synthesis and antileukemic activity of E-ring-modified (RS)-camptothecin analogues
Ejima,Terasawa,Sugimori,Ohsuki,Matsumoto,Kawato,Yasuoka,Tagawa
, p. 683 - 688 (2007/10/02)
Several E-ring-modified analogues of (RS)-camptothecin were synthesized by total synthesis via Friedlander condensation and evaluated for cytotoxicity and antitumor activity against P388 mouse leukemia cells. Among them, (RS)-20-deoxyamino-7-ethyl-10-meth