142072-65-9Relevant articles and documents
Expeditious and Efficient Annulation Protocol for the Synthesis of α,β-Unsaturated δ-Lactones from β-Keto Esters
Nangia, A.,Rao, P. Bheema
, p. 2375 - 2378 (2007/10/02)
β-Keto esters 6a-e are transformed into β-keto alcohols 7a-e, which are homologated to phosphonates 9a-e.Intramolecular Horner-Wadsworth-Emmons reaction affords δ-lactones 10a-d in excellent overall yields. Key words: δ-Lactones; β-Keto esters; Intramolecular; Phosphonates; Horner-Wadsworth-Emmons