1420904-39-7Relevant articles and documents
Iron-Catalyzed Oxidative Coupling of Indoline-2-ones with Aminobenzamides via Dual C-H Functionalization
Lai, Yi-Huan,Wu, Run-Shi,Huang, Jie,Huang, Jun-Yu,Xu, Da-Zhen
supporting information, p. 3825 - 3829 (2020/05/18)
We describe an unprecedented dual C-H functionalization of indolin-2-one via an oxidative C(sp3)-H/N-H/X-H (X = N, C, S) cross-coupling protocol, which is catalyzed by a simple iron salt under mild and ligand-free conditions and employs air (molecular oxygen) as the terminal oxidant. This method is readily applicable for the construction of tetrasubstituted carbon centers from methylenes and provides a wide variety of spiro N-heterocyclic oxindoles.