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1421919-75-6

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1421919-75-6 Usage

Description

(Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3,3is a complex organic compound with a unique molecular structure. It is characterized by the presence of a triazole ring and trifluoromethyl groups, which may contribute to its potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
(Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3,3is used as a potential therapeutic agent for various diseases due to its unique molecular structure and properties. The triazole ring and trifluoromethyl groups may provide specific interactions with biological targets, making it a promising candidate for drug development.
Used in Chemical Research:
In the field of chemical research, (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3,3can be used as a starting material or intermediate for the synthesis of more complex molecules with potential applications in various industries, such as materials science, agrochemistry, and pharmaceuticals.
Used in Material Science:
The unique properties of (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3,3may also make it suitable for use in the development of new materials with specific characteristics, such as improved stability, reactivity, or selectivity. These materials could have applications in various industries, including electronics, coatings, and adhesives.

references

[1]. ranganathan p, yu x, na c, et al. preclinical activity of a novel crm1 inhibitor in acute myeloid leukemia. blood, 2012, 120(9): 1765-1773. [2]. schmidt j, braggio e, kortuem km, et al. genome-wide studies in multiple myeloma identify xpo1/crm1 as a critical target validated using the selective nuclear export inhibitor kpt-276. leukemia, 2013, 27(12): 2357-2365.

Check Digit Verification of cas no

The CAS Registry Mumber 1421919-75-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,1,9,1 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1421919-75:
(9*1)+(8*4)+(7*2)+(6*1)+(5*9)+(4*1)+(3*9)+(2*7)+(1*5)=156
156 % 10 = 6
So 1421919-75-6 is a valid CAS Registry Number.

1421919-75-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one

1.2 Other means of identification

Product number -
Other names KPT-276

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1421919-75-6 SDS

1421919-75-6Downstream Products

1421919-75-6Relevant articles and documents

NUCLEAR TRANSPORT MODULATORS AND USES THEREOF

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Paragraph 00326, (2015/01/07)

The present invention relates to compounds of Structural Formulas (I), (II) and (III): or their pharmaceutically acceptable salts; pharmaceutical compositions comprising the compounds of Structural Formulas (I), (II) and (III); and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRMl activity. The values for the variables in Structural Formulas (I), (II) and (III) are as described and defined herein.

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