1422045-80-4

Basic information

• Product Name: benzyl ((1R,3S)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)methylcarbamate
• Synonyms: benzyl ((1R,3S)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)methylcarbamate
• CAS NO: 1422045-80-4
• Molecular Weight: 426.342
• Mol File: 1422045-80-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl ((1R,3S)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)methylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl ((1R,3S)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)methylcarbamate(1422045-80-4)
• EPA Substance Registry System: benzyl ((1R,3S)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)methylcarbamate(1422045-80-4)

Safety Data

• Hazardous Substances Data: 1422045-80-4(Hazardous Substances Data)

Upstream product

• 1338922-82-9 (1R,3S)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-ol 
• 85662-98-2 3-(3',4'-dichlorophenyl)-indan-1-one 
• 95-50-1 1,2-dichloro-benzene 
• 621-82-9 Cinnamic acid 
• 1422045-79-1 benzyl ((1R,3S)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-inden-1-yl)carbamate 
• 74-88-4 methyl iodide 
• 1422045-78-0 (1R,3S)-1-(benzyloxy)-3-(3,4-dichlorophenyl)-2,3-dihydro-1H-indene 

Downstream Products

• 86939-10-8 indatraline 

Relevant articles and documents

Asymmetric total synthesis of (+)-indatraline via diastereoselective amination of chiral ethers using chlorosulfonyl isocyanate

A concise asymmetric total synthesis of (+)-indatraline from readily available cinnamic acid is described. The key steps include Corey's oxazaborolidine-catalyzed asymmetric carbonyl reduction and a highly stereoselective amination of chiral benzylic ether with retention of stereochemistry using chlorosulfonyl isocyanate.