142326-67-8Relevant articles and documents
Antagonists of gonadotropin releasing hormone
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, (2008/06/13)
PCT No. PCT/US97/08479 Sec. 371 Date Nov. 12, 1998 Sec. 102(e) Date Nov. 12, 1998 PCT Filed May 16, 1997 PCT Pub. No. WO97/44321 PCT Pub. Date Nov. 27, 1997There are disclosed compounds of formula (I) and pharmaceutical acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related conditions.
Hydroxyquinolone derivatives compounds which have pharmaceutical utility
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, (2008/06/13)
This present invention relates to a class of 4-hydroxy-2-(1H)-quinolones which are substituted in the 3-position by an optionally substituted aryl substituent. These compounds are selective non-competitive antagonists of N-methyl-D-aspartate (NMDA) receptors.