1423778-31-7

Basic information

• Product Name: 5-methoxy-2-(phenylethynyl)quinoline
• Synonyms: 5-methoxy-2-(phenylethynyl)quinoline
• CAS NO: 1423778-31-7
• Molecular Weight: 259.307
• Mol File: 1423778-31-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-methoxy-2-(phenylethynyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxy-2-(phenylethynyl)quinoline(1423778-31-7)
• EPA Substance Registry System: 5-methoxy-2-(phenylethynyl)quinoline(1423778-31-7)

Safety Data

• Hazardous Substances Data: 1423778-31-7(Hazardous Substances Data)

Upstream product

• 90924-16-6 5--methoxyquinoline N--oxide 
• 578-67-6 quinolin-5-ol 
• 6931-19-7 5-methoxyquinoline 
• 1423778-34-0 2-(phenylethynyl)quinoline-5-ol 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 1352192-11-0 quinolin-5-yl pivalate 
• 1423778-70-4 2-chloroquinoline-5-yl pivalate 
• 1423778-32-8 2-(phenylethynyl)quinoline-5-yl pivalate 
• 536-74-3 phenylacetylene 

Relevant articles and documents

Potassium Hydroxide-Catalyzed Alkynylation of Heteroaromatic N-Oxides with Terminal Alkynes

An efficient potassium hydroxide-catalyzed alkynylation of heteroaromatic N-oxides under transition-metal-free conditions with the assistance of visible-light has been developed. Various C2-alkynylheterocycles were obtained in up to 92% yield with good functional group tolerance. This new method is operational simple, highly efficient, atom economic, and environmental friendly. (Figure presented.).

2-(Substituted ethynyl)quinoline Derivatives as mGLUr5 Antagonists

Provided is a 2-(substituted ethynyl)quinoline derivative having an mGluR5 antagonistic activity and pharmaceutically acceptable salts thereof. The compound of the present invention can be useful as a medicament for treating and preventing mGluR5 receptor