1424329-92-9

Basic information

• Product Name: C₂₂H₂₂Cl₂N₄O₂
• Synonyms: C₂₂H₂₂Cl₂N₄O₂
• CAS NO: 1424329-92-9
• Molecular Weight: 445.348
• Mol File: 1424329-92-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₂Cl₂N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₂Cl₂N₄O₂(1424329-92-9)
• EPA Substance Registry System: C₂₂H₂₂Cl₂N₄O₂(1424329-92-9)

Safety Data

• Hazardous Substances Data: 1424329-92-9(Hazardous Substances Data)

Upstream product

• 27006-76-4 5-chloro-4-formyl-1,3-dimethylpyrazole 
• 576-24-9 2,3-dichlorophenol 
• 1152560-16-1 C₁₂H₁₀Cl₂N₂O₂ 
• 1152566-35-2 C₁₂H₁₀Cl₂N₂O₃ 
• 13078-04-1 anabasine 

Relevant articles and documents

Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries

Optimization of a high-throughput screening hit led to the discovery of a new series of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as highly potent agonists of TGR5. This novel chemotype was rapidly developed through iterative combinatorial library synthesis. It was determined that in vitro agonist potency correlated with functional activity data from human peripheral blood monocytes.