142559-23-7Relevant articles and documents
Asymmetric Michael additions of Grignard reagents to cinnamamides deriving from N-alkyl (R)-(-)-2-aminobutan-1-ol
Touet,Baudouin,Brown
, p. 587 - 590 (2007/10/02)
Reaction of cinnamoyl chloride with various N-alkyl derivatives of (R)-(-)-2-aminobutan-1-ol (a readily available reagent) afforded the corresponding cinnamamides. Michael additions of Grignard reagents to the latter, followed by acidic hydrolysis, yielde