1425925-90-1

Basic information

• Product Name: (1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride
• CAS NO: 1425925-90-1
• Molecular Weight: 234.125
• Mol File: 1425925-90-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride(1425925-90-1)
• EPA Substance Registry System: (1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride(1425925-90-1)

Safety Data

• Hazardous Substances Data: 1425925-90-1(Hazardous Substances Data)

Upstream product

• 1425925-89-8 (R,E)-N-((S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-ylidene)-2-methylpropane-2-sulfinamide 
• 42348-86-7 5-chloro-1-indanone 

Relevant articles and documents

INHIBITORS OF NEDD8-ACTIVATING ENZYME

Disclosed are chemical entities which are inhibitors of Nedd8-activating enzyme (NAE), namely, the compound {(1S,2S,4R)-4-[(6-{[(1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-yl]amino}pyrimidin-4-yl)oxy]-2-hydroxycyciopentyl}methyl sulfamate and pharmaceutically acceptable salts thereof; solid state forms thereof; and prodrugs thereof. Also disclosed are methods of using the chemical entities to treat disorders such as cancer.