1426079-95-9

Basic information

• Product Name: 2-(3,4-dimethylphenyl)-3-methylimidazo[1,2-a]pyridine
• Synonyms: 2-(3,4-dimethylphenyl)-3-methylimidazo[1,2-a]pyridine
• CAS NO: 1426079-95-9
• Molecular Weight: 236.316
• Mol File: 1426079-95-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(3,4-dimethylphenyl)-3-methylimidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dimethylphenyl)-3-methylimidazo[1,2-a]pyridine(1426079-95-9)
• EPA Substance Registry System: 2-(3,4-dimethylphenyl)-3-methylimidazo[1,2-a]pyridine(1426079-95-9)

Safety Data

• Hazardous Substances Data: 1426079-95-9(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 1522130-09-1 C₁₃H₁₇NO₂ 
• 504-29-0 2-aminopyridine 
• 79-24-3 Nitroethane 
• 5973-71-7 3,4-dimethylbenzaldehyde 
• 147102-60-1 1,2-Dimethyl-4-((E)-2-nitro-propenyl)-benzene 

Relevant articles and documents

Polyethylene gylcol (PEG-400) as an efficient and recyclable reaction medium for one-pot three-component synthesis of imidazo[1,2-a]pyridine derivatives

Polyethylene glycol (PEG) was found to be an inexpensive nontoxic and effective medium for the one-pot three-component synthesis of imidazo[1,2-a]pyridine derivatives under catalyst-free conditions in excellent yields. Environmental acceptability, low cost, high yields and recyclability of the polyethylene glycol are the important features of this protocol.

Iron(III)-catalyzed denitration reaction: One-pot three-component synthesis of imidazo[1,2-a]pyridine derivatives

An iron(III)-catalyzed one-pot three-component cross-coupling nitration reaction of 2-aminopyridines, aldehydes and nitroalkanes, straightforwardly forms imidazo[1,2-a]pyridine derivatives and is described in this report. The system shows good functional-group tolerance and proceeds smoothly in moderate to good yields. An iron(III)-catalyzed one-pot three-component cross-coupling nitration reaction of 2-aminopyridines, aldehydes, and nitroalkane, leading to the straightforward formation of imidazo[1,2-a]pyridine derivatives has been reported. In this procedure, the starting materials are commercially available. The system shows good functional-group tolerance and proceeds smoothly in moderate to good yields. Copyright