1426343-20-5Relevant articles and documents
Efficient construction of proline-containing β-turn mimetic cyclic tetrapeptides via CuAAC macrocyclization
Chouhan, Gagan,James, Keith
, p. 1206 - 1209 (2013/05/21)
A range of macrocyclic β-turn mimetic tetrapeptides was prepared by efficient copper-tris(triazole) ligand complex catalyzed azide-alkyne "click" macrocyclizations in good to high yields. Preliminary conformational studies using X-ray crystallography and NMR spectroscopy demonstrated the presence of intramolecular H-bonds characteristic of β-turns in these cyclic tetrapeptides.