1426437-54-8Relevant articles and documents
NHC-initiated cascade, metal-free synthesis of quinoxaline derivatives under solvent-free conditions
Gao, Lijiu,Liu, Rui,Yu, Chenxia,Yao, Changsheng,Li, Tuanjie,Xiao, Zhaoxin
, p. 2131 - 2138 (2014)
2,3-Diaryl quinoxaline derivatives have been efficiently synthesized by cascade, metal-free, and solvent-free reaction of aryl aldehydes with aryl 1,2-diamines initiated by N-heterocyclic carbene. Compared with reported methods, this procedure has the advantages of easy work-up, reduced energy consumption, and elimination of solvent waste, hazards, and toxicity. A group of potentially bioactive compounds has been prepared for biomedical screening.