1426580-91-7Relevant articles and documents
Total synthesis of acerogenins E, G and K, and centrolobol
Ogura, Tetsuhiro,Usuki, Toyonobu
, p. 2807 - 2815 (2013)
The first total synthesis of the diarylheptanoid acerogenins E and K, isolated from Acer nikoense MAXIM., is described. Formation of the 13-membered m,m-cyclophane skeleton was successfully achieved on the basis of a domino process involving a Miyaura arylborylation-intramolecular Suzuki reaction. The cyclization precursor was prepared via a Wittig reaction and Claisen-Schmidt condensation, which proceeded in moderate yields. The total synthesis of acerogenin G and centrolobol was also achieved from a common synthetic intermediate.
