1427054-96-3Relevant articles and documents
Concise synthesis of tylophorine
Lin, Qi-Xian,Ho, Tse-Lok
, p. 2996 - 3001 (2013)
The phenanthroindolizidine alkaloid tylophorine has been synthesized in the (R)- and racemic forms. One of the routes involves three steps from a known compound employing a Stevens rearrangement as the pivotal reaction. The phenanthrene moiety was constructed by either a base-catalyzed cyclization of 2-alkynylbiphenyls or a double Suzuki coupling of a 2,2′-dibromobiphenyl with vic-bis(pinacolatoboryl)alkene in other routes.