1427219-10-0

Basic information

• Product Name: (R)-2-((S)-2-benzhydrylpyrrolidin-1-yl)-1-phenylethanamine
• Synonyms: (R)-2-((S)-2-benzhydrylpyrrolidin-1-yl)-1-phenylethanamine
• CAS NO: 1427219-10-0
• Molecular Weight: 356.511
• Mol File: 1427219-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-((S)-2-benzhydrylpyrrolidin-1-yl)-1-phenylethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-((S)-2-benzhydrylpyrrolidin-1-yl)-1-phenylethanamine(1427219-10-0)
• EPA Substance Registry System: (R)-2-((S)-2-benzhydrylpyrrolidin-1-yl)-1-phenylethanamine(1427219-10-0)

Safety Data

• Hazardous Substances Data: 1427219-10-0(Hazardous Substances Data)

Upstream product

• 1427219-08-6 (R)-2-amino-1-((S)-2-benzhydrylpyrrolidin-1-yl)-2-phenylethanone 
• 1427219-07-5 benzyl ((R)-2-((S)-2-benzhydrylpyrrolidin-1-yl)-2-oxo-1-phenylethyl)carbamate 
• 17609-52-8 Z-D-phenylglycine 
• 22348-31-8 (S)-2-(diphenylmethyl)pyrrolidine 

Relevant articles and documents

Synthesis and application of L-proline and R-phenylglycine derived organocatalysts for direct asymmetric Michael addition of cyclohexanone to nitroalkenes

Novel R-phenylglycine derived organocatalysts were prepared from the reaction of Cbz-R-phenylglycine with indoline, pyrrolidine, or (S)-(-)-2-(diphenylmethyl)pyrrolidine in 3 steps. The asymmetric Michael addition of cyclohexanone to nitroolefins was investigated using R-phenylglycine derivatives along with L-prolinamides as chiral catalysts. The desired products were obtained in excellent yields with enantioselectivities up to 90% ee and diastereomeric ratio up to 98:2 of the syn addition product. TUeBITAK, 2012.