142730-67-4Relevant articles and documents
Carbon-carbon bond-forming enantioselective synthesis of chiral organosilicon compounds by rhodium/chiral diene-catalyzed asymmetric 1,4-addition reaction
Shintani, Ryo,Okamoto, Kazuhiro,Hayashi, Tamio
, p. 4757 - 4759 (2007/10/03)
(Chemical Equation Presented) A new synthetic method for chiral organosilicon compounds through a rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to β-silyl α,β-unsaturated carbonyl compounds has been developed. By employing (R,R)-Bn-bod * as a ligand, a range of arylboronic acids can be coupled with these substrates in very high enantiomeric excess. The resulting β-silyl 1,4-adducts can be converted to β-hydroxy carbonyl compounds or allylsilanes while retaining their stereochemical information.
Catalytic Asymmetric Addition of Polyfunctional Dialkylzincs to β-Stannylated and β-Silylated Unsaturated Aldehydes
Ostwald, Roswitha,Chavant, Pierre-Yves,Stadtmueller, Heinz,Knochel, Paul
, p. 4143 - 4153 (2007/10/02)
The addition of functionalized dialkylzincs to readily available β-stannylated or β-silylated unsaturated aldehydes in the presence of a catalytic amount of (1R,2R)-1,2-bis(trifluorosulfonamido)cyclohexane (8 mol percent) provides chiral allylic alcohols
