1428321-23-6Relevant articles and documents
Synthesis of 1,3-dehydroadamantanes possessing alkyl, phenyl, and alkoxy substituents by intramolecular wurtz-type coupling reaction of 1,3-dibromoadamantanes
Inomata, Sotaro,Harada, Yusuke,Nakamura, Yuya,Nakamura, Taisuke,Ishizone, Takashi
, p. 3332 - 3340 (2013)
A series of highly strained [3.3.1]propellane derivatives, 1,3-dehydroadamantanes (DHAs) possessing alkyl, phenyl, and alkoxy substituents, such as 5-butyl, 5-hexyl, 5-octyl, 5-phenyl, 5-methoxy, 5-butoxy, 5,7-dimethyl, 5-ethyl-7-hexyl, 5,7-dibutyl-, 5-butyl-7-isobutyl, 5-butyl-7-hexyl, 5-butyl-7-phenyl, 5-butyl-7-methoxy, and 5-butoxy-7-butyl, were synthesized in several gram amounts. The 1,3-dibromoadamantanes carrying alkyl, phenyl, and alkoxy substituents were converted into the corresponding DHAs via the intramolecular Wurtz-type coupling reactions with lithium metal in THF in 21-81% yields. Georg Thieme Verlag Stuttgart . New York.