142896-66-0

Basic information

• Product Name: (2R,4S)-1-(4-tolylsulfonyl)-2-(1-hydroxyethyl)-4-hydroxypyrrolidine
• CAS NO: 142896-66-0
• Molecular Weight: 285.364
• Mol File: 142896-66-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,4S)-1-(4-tolylsulfonyl)-2-(1-hydroxyethyl)-4-hydroxypyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4S)-1-(4-tolylsulfonyl)-2-(1-hydroxyethyl)-4-hydroxypyrrolidine(142896-66-0)
• EPA Substance Registry System: (2R,4S)-1-(4-tolylsulfonyl)-2-(1-hydroxyethyl)-4-hydroxypyrrolidine(142896-66-0)

Safety Data

• Hazardous Substances Data: 142896-66-0(Hazardous Substances Data)

Upstream product

• 141621-11-6 1-[(2R,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-ethanol 

Downstream Products

• 141621-13-8 C₂₇H₃₁NO₈S₃ 
• 141621-15-0 7-((1R,4R)-5-Benzyl-6-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-1-tert-butyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 141871-22-9 (1R,4R)-2-Benzyl-3-methyl-2,5-diaza-bicyclo[2.2.1]heptane; hydrobromide 
• 141621-14-9 (6R)-(1R,4R)-6-methyl-2-(p-toluenesulfonyl)-5-phenylmethyl-2,5-diazabicyclo<2.2.1>heptane 
• 142928-73-2 7-((1R,4R,6R)-5-Benzyl-6-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-1-cyclopropyl-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 143004-99-3 7-((1R,4R,6S)-5-Benzyl-6-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-1-cyclopropyl-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 141661-85-0 7-<(1R,4R,6R)-5-(phenylmethyl)-6-methyl-2,5-diazabicyclo<2.2.1>heptan-2-yl>-1-(1,1-dimethylethyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-napthyridine-3-carboxylic acid ethyl ester 
• 141621-14-9 (1R,4R,6R)-6-methyl-5-(phenylmethyl)-2-(4-tolylsulfonyl)-2,5-diazabicyclo<2.2.1>heptane 
• 142896-69-3 (1R,4R,6R)-2-(trifluoroacetyl)-5-(phenylmethyl)-6-methyl-2,5-diazabicyclo<2.2.1>heptane 
• 143004-12-0 (1R,4R,6S)-2-(trifluoroacetyl)-5-(phenylmethyl)-6-methyl-2,5-diazabicyclo<2.2.1>heptane 
• 142896-64-8 (1R,4R,6R)-2-(trifluoroacetyl)-6-methyl-2,5-diazabicyclo<2.2.1>heptane 
• 143004-11-9 (1R,4R,6S)-2-(trifluoroacetyl)-6-methyl-2,5-diazabicyclo<2.2.1>heptane 
• 143005-00-9 7-((1R,4R,6S)-5-Benzyl-6-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 142928-75-4 7-((1R,4R,6S)-5-Benzyl-6-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-1-tert-butyl-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 

Relevant articles and documents

PREPARATION OF (6R)- AND (6S)-(1R,4R)-6-METHYL-2-(p-TOLUENESULFONYL)-5-PHENYLMETHYL-2,5-DIAZABICYCLOHEPTANES, INTERMEDIATES IN A SYNTHESIS OF NEW QUINOLONES

An efficjent chiral synthesis of both diastereoisomers (2a) and (2b) was preformed using trans-4-hydroxy-L-proline as starting material.These bridged piperazines were used in the preparation of quinolones.