1429058-85-4

Basic information

• Product Name: (3aS,4S,9bS,αR)-N(1)-(α-methyl-4''-methoxybenzyl)-4-(2'-methoxy-2'-oxoethyl)-8-bromo-2,3,3a,4,5,9bhexahydro-1H-pyrrolo[3,2-c]quinolin-2-one
• CAS NO: 1429058-85-4
• Molecular Weight: 473.366
• Mol File: 1429058-85-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3aS,4S,9bS,αR)-N(1)-(α-methyl-4''-methoxybenzyl)-4-(2'-methoxy-2'-oxoethyl)-8-bromo-2,3,3a,4,5,9bhexahydro-1H-pyrrolo[3,2-c]quinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3aS,4S,9bS,αR)-N(1)-(α-methyl-4''-methoxybenzyl)-4-(2'-methoxy-2'-oxoethyl)-8-bromo-2,3,3a,4,5,9bhexahydro-1H-pyrrolo[3,2-c]quinolin-2-one(1429058-85-4)
• EPA Substance Registry System: (3aS,4S,9bS,αR)-N(1)-(α-methyl-4''-methoxybenzyl)-4-(2'-methoxy-2'-oxoethyl)-8-bromo-2,3,3a,4,5,9bhexahydro-1H-pyrrolo[3,2-c]quinolin-2-one(1429058-85-4)

Safety Data

• Hazardous Substances Data: 1429058-85-4(Hazardous Substances Data)

Upstream product

• 1429058-82-1 (3aR,9bS,αR)-N(1)-(α-methyl-4'-methoxybenzyl)-4-hydroxy-N(5)-(tert-butoxycarbonyl)-8-bromo-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-c]quinolin-2-one 
• 66416-72-6 4-bromo-2-iodoaniline 
• 1161719-82-9 (E)-tert-butyl 3-(2-amino-5-bromophenyl)acrylate 
• 1429058-76-3 tert-butyl (E)-3-(2'-N,N-diallylamino-5'-bromophenyl)propenoate 
• 1429058-77-4 tert-butyl (3S,αR)-3-[N-allyl-N-(α-methyl-4''-methoxybenzyl)amino]-3-(2'-N,N-diallylamino-5'-bromophenyl)propanoate 
• 1429058-78-5 tert-butyl (2R,3S,αR)-2-(2'-methoxy-2'-oxoethyl)-3-[N-allyl-N-(α-methyl-4'''-methoxybenzyl)amino]-3-(2''-N,N-diallylamino-5''-bromophenyl)propanoate 
• 1429058-79-6 C₂₅H₃₃BrN₂O₅ 
• 1429058-80-9 C₂₀H₁₉BrN₂O₃ 
• 1429058-81-0 (3aR,9bS,αR)-N(1)-(4'-methoxy-α-methylbenzyl)-5-(tert-butoxycarbonyl)-8-bromo-2,3,3a,4,5,9bhexahydro-1H-pyrrolo[3,2-c]quinolin-2,4-dione 

Relevant articles and documents

Asymmetric synthesis of (-)-martinellic acid

A high-yielding total asymmetric synthesis of (-)-martinellic acid is reported. The conjugate addition of lithium (R)-N-allyl-N-(α-methyl-4- methoxybenzyl)amide to tert-butyl (E)-3-[2′-(N,N-diallylamino)-5′- bromophenyl]propenoate and alkylation of the resultant β-amino ester have been used as the key steps to install the C(9b) and C(3a) stereogenic centers, respectively, and a highly diastereoselective Wittig reaction/intramolecular Michael addition was then used to create the C(4) stereogenic center within this tricyclic molecular architecture.