142955-73-5

Basic information

• Product Name: 3-Hydroxy-N-((S)-1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid
• CAS NO: 142955-73-5
• Molecular Weight: 295.292
• Mol File: 142955-73-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Hydroxy-N-((S)-1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-N-((S)-1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid(142955-73-5)
• EPA Substance Registry System: 3-Hydroxy-N-((S)-1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid(142955-73-5)

Safety Data

• Hazardous Substances Data: 142955-73-5(Hazardous Substances Data)

Upstream product

• 22839-47-0 aspartame 

Relevant articles and documents

Reactivite du nitrite de sodium. V. Action sur les amino-acides, peptides et proteines

The action of sodium nitrite on various amino-acids was re-examined in conditions approximating to a biological medium. 13C-NMR provides evidence of the existence of intramolecular ring closures and the formation of 5-membered rings with ornithine, citrulline and arginine.The reaction of cystine shows the opening of the sulphur bridges, whereas cysteine leads to the formation of carboxy-thiiran and 3-sulpho-lactic acid.The hydrolysis of the amide bonds of asparagine and glutamine is complete whereas the peptides studied - carnosine and aspartam - do not undergo hydrolysis of the peptide linkage.However, the first deamination of glutathion (γ-Glu-Cys-Gly) induces the peptide link to be broken and a cyclization with the formation of lactone to occur.A second deamination takes place on the cysteinyl residue released and allows the formation of a thiiran by intramolecular cyclization with the thiol group.The formation of thiiran was also observed with oxidized glutathion which has an S-S bridge.Finally, the formation of nitrosamines was detected by 15N-NMR during the reaction of sodium nitrite with two commercial products available to the general public.