1429749-50-7Relevant articles and documents
Selective and sensitive chromogenic and fluorogenic detection of sulfur mustard in organic, aqueous and gaseous medium
Kumar, Vinod,Rana, Hemlata
, p. 91946 - 91950 (2015/11/17)
We present a highly selective and sensitive detection protocol for the chemical warfare agent sulfur mustard (SM). The chromogenic and fluorogenic system uses a squaraine dye (SQ) that not only detects SM but also discriminates it from other chemical warfare agents (CWAs) and potent electrophilic interferents. A water soluble dithiol, 2-(3,5-bis(mercaptomethyl)phenoxy)acetic acid 1, in the presence and absence of SM, behaves differently towards the squaraine dye (SQ) to give different chromogenic and fluorogenic responses. With an aim to mimic real-life scenarios for the onsite and offsite detection, the sensing protocol was further implemented in spiked water and soil samples, on surfaces, and in the gas phase. The lower detection limit (much lower than the lethal dose) of both visual inspection and the fluorescence technique will be highly useful to mankind in order to sensitively detect SM.
A selective and sensitive chromogenic and fluorogenic detection of a sulfur mustard simulant
Kumar, Vinod,Anslyn, Eric V.
, p. 4292 - 4297 (2013/10/22)
A simple and highly selective chromogenic and fluorogenic detection of sulfur mustard (SM) simulants is reported. Dithiol 1, in the presence and absence of a mustard simulant behaves differently toward a squaraine dye (SQ), and thus provides a visual and spectroscopic signal for mustard gas. The sensor responds to the SM simulant, but not to the O-analog of mustard stimulant or nerve agent mimics and other electrophilic agents. The visual and fluorescent detection with less than 50 μM of SM simulant shows good sensitivity. The utility of the sensor was demonstrated by analysis of SM simulant on surfaces, in soil, and in the gas phase. The Royal Society of Chemistry 2013.
