142977-53-5

Basic information

• Product Name: Pyridine, 2-[(1,1-dichloro-2,2-difluorooctyl)thio]-
• CAS NO: 142977-53-5
• Molecular Formula: C13H17Cl2F2NS
• Molecular Weight: 328.253
• Mol File: 142977-53-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-[(1,1-dichloro-2,2-difluorooctyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-[(1,1-dichloro-2,2-difluorooctyl)thio]-(142977-53-5)
• EPA Substance Registry System: Pyridine, 2-[(1,1-dichloro-2,2-difluorooctyl)thio]-(142977-53-5)

Safety Data

• Hazardous Substances Data: 142977-53-5(Hazardous Substances Data)

Upstream product

• 79-35-6 1,1'-dichloro-2,2'-difluoroethene 
• 91233-20-4 1-(hexylcarbonyloxy)pyridine-2(1H)-thione 

Relevant articles and documents

A facile preparation method for α,α-difluoroalkanecarboxylic acids and esters. A formal difluoromethylene insertion to alkanecarboxylic acids using radical reaction

Various alkyl radicals generated by the photoreaction of a series of Barton esters reacted with 1,1-dichloro-2,2-difluoroethene to give radical adducts as the major product accompanied with self-trapping products. Primary, secondary, tertiary, benzyl, and some unsaturated alkyl radicals as well as those with another functional group such as ether, carbonyl, and azide were applicable. Barton esters of diacids also afford 1:2 adducts with a small amount of 1:1 adducts and bis-self-trapping products except for the succinic case. These adducts were hydrolyzed with AgNO3/H2O-THF to α,α-difluoroalkanecarboxylic acids and methanolyzed with AgNO3/MeOH to the corresponding methyl esters. 4-Azido-2,2-difluorobutylic acid and the methyl ester were converted to difluoro-GABA and difluoro-γ-lactams.