142994-45-4 Usage
Description
(R)-N-Fmoc-(3-Pyridyl)alanine, also known as Fmoc-d-3-pyridylalanine, is a non-natural, chiral amino acid building block derived from the naturally occurring (S)-enantiomer. It is characterized by its white crystalline powder form and is widely utilized in the synthesis of peptides. The growing peptide drug market emphasizes the importance of fast and reliable peptide synthesis, making (R)-N-Fmoc-(3-Pyridyl)alanine a valuable compound in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
(R)-N-Fmoc-(3-Pyridyl)alanine is used as an amino acid building block for the synthesis of peptides. Its application is crucial in the development of new peptide-based drugs, which are increasingly in demand due to their potential therapeutic benefits and specificity.
Used in Research and Development:
In the field of research and development, (R)-N-Fmoc-(3-Pyridyl)alanine serves as a key component in the design and synthesis of novel peptide sequences. Its unique properties allow scientists to explore new avenues in drug discovery and the development of targeted therapeutics.
Used in Drug Delivery Systems:
Similar to gallotannin, (R)-N-Fmoc-(3-Pyridyl)alanine can be employed in the development of innovative drug delivery systems. These systems aim to improve the bioavailability, delivery, and therapeutic outcomes of peptide-based drugs, making them more effective and targeted in treating various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 142994-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,9,9 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 142994-45:
(8*1)+(7*4)+(6*2)+(5*9)+(4*9)+(3*4)+(2*4)+(1*5)=154
154 % 10 = 4
So 142994-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C23H20N2O4/c26-22(27)21(12-15-6-5-11-24-13-15)25-23(28)29-14-20-18-9-3-1-7-16(18)17-8-2-4-10-19(17)20/h1-11,13,20-21H,12,14H2,(H,25,28)(H,26,27)/p-1/t21-/m1/s1
142994-45-4Relevant articles and documents
Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives
Moussa, Amer,Meffre, Patrick,Martinez, Jean,Rolland, Valerie
experimental part, p. 1339 - 1348 (2012/09/07)
Enantiomerically pure 2-, 3- or 4-pyridylalanine (pya) and 2-azatyrosine (azatyr) are known to present various biological activities. After incorporation into appropriate peptide sequences, these heterocyclic non natural α-amino acids could behave as new substrates or inhibitors of elastase from Pseudomonas aeruginosa. This enzyme is known to be involved in nosocomial infections and infections related to the cystic fibrosis disease. New efficient chemoenzymatic preparations of those compounds using α-chymotrypsin (α-CT) are presented. Springer-Verlag 2011.
