143017-40-7

Basic information

• Product Name: 4-Piperidinol, 1-[2-(1,3-dioxolan-2-yl)ethyl]-4-(4-fluorophenyl)-
• CAS NO: 143017-40-7
• Molecular Formula: C16H22FNO3
• Molecular Weight: 295.354
• Mol File: 143017-40-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Piperidinol, 1-[2-(1,3-dioxolan-2-yl)ethyl]-4-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinol, 1-[2-(1,3-dioxolan-2-yl)ethyl]-4-(4-fluorophenyl)-(143017-40-7)
• EPA Substance Registry System: 4-Piperidinol, 1-[2-(1,3-dioxolan-2-yl)ethyl]-4-(4-fluorophenyl)-(143017-40-7)

Safety Data

• Hazardous Substances Data: 143017-40-7(Hazardous Substances Data)

Upstream product

• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 3888-65-1 4-(4-fluorophenyl)piperidin-4-ol 

Downstream Products

• 143017-57-6 (+)-5(S),6(R)-endo-4-(4-fluorophenyl)-6-hydroxy-1-azabicyclo<3.3.1>non-3-ene 
• 143017-58-7 (-)-5(R),6(S)-endo-4-(4-fluorophenyl)-6-hydroxy-1-azabicyclo<3.3.1>non-3-ene 

Relevant articles and documents

INTRAMOLECULAR CYCLIZATION WITH OXOCARBENIUM ION. SYNTHESIS OF 1-AZABICYCLONONENE AND OCTENE DERIVATIVES

Hydroxy- and aryl-substituted 1-azabicyclononene and octene derivatives have been synthesized by the intramolecular cationic cyclization of 4-aryl-1,2,5,6-tetrahydropyridines bearing an acetal moiety in the nitrogen substituent.Factors governing the stereoselectivity of the ring closure step have been disclosed.Two compounds were resolved into the enantiomers and the absolute configuration of one of them was deduced from CD investigations.Among the new compounds substances with valuable antiamnesic effect have been found.