1430220-99-7

Basic information

• Product Name: (E)-N-benzyl-3-(thiophen-3-yl)acrylamide
• Synonyms: (E)-N-benzyl-3-(thiophen-3-yl)acrylamide
• CAS NO: 1430220-99-7
• Molecular Weight: 243.329
• Mol File: 1430220-99-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-N-benzyl-3-(thiophen-3-yl)acrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N-benzyl-3-(thiophen-3-yl)acrylamide(1430220-99-7)
• EPA Substance Registry System: (E)-N-benzyl-3-(thiophen-3-yl)acrylamide(1430220-99-7)

Safety Data

• Hazardous Substances Data: 1430220-99-7(Hazardous Substances Data)

Upstream product

• 1195-52-4 trans-3-(3-thienyl)acrylic acid 
• 100-46-9 benzylamine 

Relevant articles and documents

Direct synthesis of amides from carboxylic acids and amines using B(OCH2CF3)3

B(OCH2CF3)3, prepared from readily available B2O3 and 2,2,2-trifluoroethanol, is as an effective reagent for the direct amidation of a variety of carboxylic acids with a broad range of amines. In most cases, the amide products can be purified by a simple filtration procedure using commercially available resins, with no need for aqueous workup or chromatography. The amidation of N-protected amino acids with both primary and secondary amines proceeds effectively, with very low levels of racemization. B(OCH2CF3)3 can also be used for the formylation of a range of amines in good to excellent yield, via transamidation of dimethylformamide.