1430414-15-5

Basic information

• Product Name: C₂₀H₂₀ClF₂N₃O₅S
• Synonyms: C₂₀H₂₀ClF₂N₃O₅S
• CAS NO: 1430414-15-5
• Molecular Weight: 487.912
• Mol File: 1430414-15-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₀ClF₂N₃O₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₀ClF₂N₃O₅S(1430414-15-5)
• EPA Substance Registry System: C₂₀H₂₀ClF₂N₃O₅S(1430414-15-5)

Safety Data

• Hazardous Substances Data: 1430414-15-5(Hazardous Substances Data)

Upstream product

• 168828-84-0 (R)-5-azidomethyl-3-(3-fluoro-4-(morpholin-4-yl)phenyl)oxazolidin-2-one 
• 85958-57-2 2-chloro-4-fluorobenzene-1-sulfonyl chloride 
• 168828-90-8 (S)-N-[[3-[3-fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]amine 

Relevant articles and documents

Synthesis, biological evaluation of new oxazolidino-sulfonamides as potential antimicrobial agents

A number of linezolid-like oxazolidino-sulfonamides (7a-y and 8a-b) were designed and synthesized with a view to develop antimicrobial agents with improved properties. Most of the synthesized compounds showed good to moderate activity against a panel of standard Gram-positive and Gram-negative bacteria and fungal strains. The compounds 7i and 7v exhibited significant activity, with a MIC value of 2.0-6.0 μg/mL against a panel of Gram-positive and Gram-negative bacteria. These compounds also showed activity against Candida albicans, with a MIC value of 4.0 μg/mL. A correlation of the antimicrobial activity with calculated lipophilicity values (C log P) is also presented.