143084-99-5Relevant articles and documents
Substrate scope in the copper-mediated construction of bis-oxindoles via a double C-H/Ar-H coupling process
Drouhin, Pauline,Hurst, Timothy E.,Whitwood, Adrian C.,Taylor, Richard J.K.
supporting information, p. 7124 - 7136 (2015/03/30)
Abstract The synthesis of bis-oxindoles via the copper(II)-mediated double cyclisation of linear bis-anilides is described. Cu(OAc)2·H2O was identified as an efficient and inexpensive catalyst for this process. In contrast to previous methods, which rely on the synthesis of the central core from existing oxindole building blocks, this new approach focusses on concurrent formation of both oxindole rings from a simple linear precursor, allowing the formation of bis-oxindoles containing a diverse range of cyclic and acyclic linkers using a single synthetic method.
Iron-catalyzed aerobic oxidative amidation of tertiary amines with carboxylic acids
Ma, Lina,Li, Yuanming,Li, Zhiping
, p. 1310 - 1315 (2015/03/18)
An oxidative amidation of tertiary amines with carboxylic acids has been developed in the presence of FeCl3·6H2O as catalyst and oxygen as oxidant. A variety of tertiary amides were obtained in good to excellent yields from inexpensive and readily available reagents. The possible reaction pathways were investigated.