1431838-48-0

Basic information

• Product Name: methyl 3-hydroxy-2-(2-phenylethyl)-propionate
• Synonyms: methyl 3-hydroxy-2-(2-phenylethyl)-propionate
• CAS NO: 1431838-48-0
• Molecular Weight: 208.257
• Mol File: 1431838-48-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-hydroxy-2-(2-phenylethyl)-propionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-hydroxy-2-(2-phenylethyl)-propionate(1431838-48-0)
• EPA Substance Registry System: methyl 3-hydroxy-2-(2-phenylethyl)-propionate(1431838-48-0)

Safety Data

• Hazardous Substances Data: 1431838-48-0(Hazardous Substances Data)

Upstream product

• 1821-12-1 4-Phenylbutyric acid 
• 67-56-1 methanol 
• 242483-39-2 2-methyl-4-phenyl-butyryl chloride 
• 1949-41-3 2-methyl-4-phenylbutanoic acid 
• 1431838-47-9 2-(2-phenylethyl)propanedioic acid monomethyl ester 

Downstream Products

• 1431838-50-4 1-benzyloxy-3-(2-phenylethyl)azetidin-2-one 
• 1431838-20-8 3-(2-phenylethyl)azetidin-2-one 
• 1431838-49-1 N-benzyloxy-3-hydroxy-2-(2-phenylethyl)propionamide 

Relevant articles and documents

Unactivated C(sp3)-H hydroxylation through palladium catalysis with H2O as the oxygen source

A novel palladium catalyzed hydroxylation of unactivated aliphatic C(sp3)-H bonds was successfully developed. Different from conventional methods, water serves as the hydroxyl group source in the reaction. This new reaction demonstrates good reactivity and broad functional group tolerance. The C-H hydroxylated products can be readily transformed into various highly valuable chemicals via known transformations. Based on experimental and theoretical studies, a mechanism involving the Pd(ii)/(iv) pathway is proposed for this hydroxylation reaction.