1431866-16-8Relevant articles and documents
The development of a one pot, regiocontrolled, three-component reaction for the synthesis of thieno[2,3-c]pyrroles
Hong, Cynthia M.,Statsyuk, Alexander V.
, p. 2932 - 2935 (2013/07/25)
A three-component reaction has been developed that allows the regioselective synthesis of thieno[2,3-c]pyrroles. The reaction is based on the ability of 2-acetyl-3-thiophenecarboxaldehyde to react with amine and thiol nucleophiles to produce the corresponding tri-substituted thieno[2,3-c]pyrroles, with water as the only by-product. The developed reaction expands the range of synthetically accessible, tri-substituted thieno[2,3-c]pyrroles. The Royal Society of Chemistry 2013.