143259-55-6Relevant articles and documents
4- And 5-aroylindoles as novel classes of potent antitubulin agents
Liou, Jing-Ping,Wu, Chang-Ying,Hsieh, Hsing-Pang,Chang, Chi-Yen,Chen, Chi-Ming,Kuo, Ching-Chuan,Chang, Jang-Yang
, p. 4548 - 4552 (2008/02/13)
A novel series of 4- and 5-aroylindole derivatives was prepared and evaluated for antitumor activity. Several compounds showed excellent antiproliferative activity as inhibitors of tubulin polymerization. Compounds 13,14,15, and 18, with IC50 v