143264-61-3

Basic information

• Product Name: Ethanone, 1-[4-[1-(difluoromethylene)pentyl]phenyl]-
• CAS NO: 143264-61-3
• Molecular Formula: C14H16F2O
• Molecular Weight: 238.277
• Mol File: 143264-61-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-[1-(difluoromethylene)pentyl]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-[1-(difluoromethylene)pentyl]phenyl]-(143264-61-3)
• EPA Substance Registry System: Ethanone, 1-[4-[1-(difluoromethylene)pentyl]phenyl]-(143264-61-3)

Safety Data

• Hazardous Substances Data: 143264-61-3(Hazardous Substances Data)

Upstream product

• 122-56-5 tributyl borane 
• 13329-40-3 4-Iodoacetophenone 
• 433-06-7 2,2,2-Trifluoroethyl p-toluenesulfonate 

Relevant articles and documents

A Facile Synthesis of Disubstituted 1,1-Difluoro-1-alkenes via Double Transmetalation of 2,2-difluorovinylboranes

2,2,2-Trifluoroethyl p-toluenesulfonate is treated with butyllithium and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which couple with aryl iodides in the presence of cuprous iodide and palladium catalyst to afford 1,1-difluoro-1-alkenes in excellent yields. Key Words: Difluoroalkene; Difluorovinylborane; Transmetalation; Coupling reaction; Palladium catalyst