143360-89-8Relevant articles and documents
Synthesis of readily cleavable immobilized 1,10-phenanthroline resins
Slough, Greg A.,Krchnak, Viktor,Helquist, Paul,Canham, Stephen M.
, p. 2909 - 2912 (2004)
(Equation Presented) 1,10-Phenanthroline is derivatized and ultimately immobilized on two different polystyrene/divinylbenzene solid supports using convenient methodology. All syntheses are amenable to semiautomatic processing and are scalable for high-throughput screening. A domino copper-catalyzed coupling-cyclization reaction is used to illustrate applicability in catalytic studies.
Synthesis of 2,3-disubstituted indoles from alkynylanilines and 2-chlorophenols using palladium–dihydroxyterphenylphosphine catalyst
Yamaguchi, Miyuki,Ogihara, Kota,Konishi, Hideyuki,Manabe, Kei
supporting information, (2020/04/15)
2,3-Disubstituted indoles bearing 2-hydroxyphenyl moieties at their C3 positions were synthesized from readily available 2-chlorophenols and alkynylanilines via aminopalladation/reductive elimination using Pd–dihydroxyterphenylphosphine catalyst. The catalyst accelerates the introduction of the 2-hydroxyphenyl group at the C3 position of the indole.
Synthesis of Polysubstituted 3-Chalcogenated Indoles through Copper(I) Iodide-Catalyzed Three-Component Domino Reactions
Gou, Rui,Zhang, Yi,Wu, Sheng-Wei,Liu, Feng
, p. 207 - 212 (2019/01/14)
Polysubstituted 3-chalcogenated indoles were synthesized by a three-component, one-pot, domino reaction of a N -(2-bromophenyl)trifluoroacetamide, a 1-alkyne, a disulfides or diselenides, CuI, and proline in DMF. In this process, tandem Sonogashira coupling, N-cyclization, and sulfenyl/selenyl electrophilic substitution occurred sequentially and smoothly to form the anticipated products in good to excellent yields (20 examples; 65-96%). Notably, no palladium catalyst was used in this catalytic system, supporting its cost effectiveness and potential industrial application.
