143427-44-5

Basic information

• Product Name: Benzenemethanol, a-(2-chloroethyl)-a-2-propenyl-
• Synonyms: 1-Chloro-3-phenyl-hex-5-en-3-ol;1-chloro-3-phenylhex-5-en-3-ol
• CAS NO: 143427-44-5
• Molecular Formula: C12H15ClO
• Molecular Weight: 210.704
• Mol File: 143427-44-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 90 °C (0.1 mmHg)
• CAS DataBase Reference: Benzenemethanol, a-(2-chloroethyl)-a-2-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(2-chloroethyl)-a-2-propenyl-(143427-44-5)
• EPA Substance Registry System: Benzenemethanol, a-(2-chloroethyl)-a-2-propenyl-(143427-44-5)

Safety Data

• Hazardous Substances Data: 143427-44-5(Hazardous Substances Data)

Upstream product

• 936-59-4 3-chloropropiophenone 
• 15336-98-8 diallyldibutyltin 
• 54655-41-3 B-allyl-1,3,2-dioxaborinane 
• 106-95-6 allyl bromide 
• 7393-43-3 tetraallyl tin 
• 72824-04-5 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1730-25-2 allylmagnesium bromide 

Downstream Products

• 1114066-14-6 1-phenethylamino-3-phenyl-hex-5-en-3-ol 
• 1110641-87-6 6-allyl-6-phenyl-3-(2-phenylcyclopropyl)-1,3-oxazinan-2-one 
• 1114084-55-7 (S)-6-allyl-3-((S)-1-(4-bromophenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1110642-01-7 (R)-6-allyl-3-((S)-1-(4-bromophenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1110642-31-3 (R)-6-allyl-3-((S)-1-(4'-fluoro-[1,1'-biphenyl]-4-yl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1321599-87-4 (R)-6-allyl-3-((S)-1-(4'-fluoro-[1,1'-biphenyl]-4-yl)propyl)-6-phenyl-1,3-oxazinan-2-one 
• 1114085-85-6 (R)-3-((S)-1-(4'-fluorobiphenyl-4-yl)propyl)-6-(3-hydroxypropyl)-6-phenyl-1,3-oxazinan-2-one 
• 1114065-84-7 (R)-3-((S)-1-(4'-fluorobiphenyl-4-yl)ethyl)-6-(3-hydroxypropyl)-6-phenyl-1,3-oxazinan-2-one 
• 1114065-78-9 (S)-3-((S)-1-(4'-fluorobiphenyl-4-yl)ethyl)-6-(2-hydroxyethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1114065-94-9 (R)-3-((S)-1-(2',4'-difluorobiphenyl-4-yl)ethyl)-6-(3-hydroxypropyl)-6-phenyl-1,3-oxazinan-2-one 
• 1114065-86-9 (S)-3-((S)-1-(2',4'-difluorobiphenyl-4-yl)ethyl)-6-(2-hydroxyethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1114065-95-0 (R)-6-allyl-3-((S)-1-(2',4'-difluoro-[1,1'-biphenyl]-4-yl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1110641-90-1 (R)-6-allyl-3-((S)-1-(4-bromophenyl)propyl)-6-phenyl-1,3-oxazinan-2-one 
• 1259034-42-8 (S)-3-((S)-1-(4-(4-(azetidin-1-yl)-3,3-dimethyl-4-oxobut-1-ynyl)phenyl)ethyl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one 

Relevant articles and documents

Hydroxyl group-assisted palladium-catalyzed lactonization of homoallylic alcohols

A convenient and highly efficient synthesis of α-methylene-γ- lactones through the palladium(II)-catalyzed lactonization of homoallylic alcohols with alkynamides has been reported. The hydroxyl group in the terminal olefins cooperates with the amide in alkynamides to promote the cyclization by suppressing the β-H elimination. This process provides a route to construct naturally occurring biologically multifunctional α-methylene-γ- lactones. The time has come to.i?lactonize: α-Methylene- γ-lactones are synthesized through the PdII-catalyzed lactonization of homoallylic alcohols with alkynamides. The hydroxyl group in the terminal olefins cooperates with the amide in alkynamides to promote the cyclization by suppressing the β-H elimination. This provides a route towards naturally occurring biologically multifunctional α-methylene- γ-lactones. Copyright

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