143521-77-1Relevant articles and documents
Synthesis and heteronuclear NMR analysis of deuterium- and tritium-labelled methylenebisphosphonic acid
Blackburn,Rosenberg,Yakovleva
, p. 3927 - 3930 (2007/10/02)
Deuterium has been substituted into the methylene group of methylenebisphosphonic acid, MDP. Analysis of the phosphorus NMR spectrum of the product shows a linear high-frequency shift on sequential mono- and di-deuteriation. The corresponding tritium labelling of MDP achieved a specific activity of 30 mCi/mmol.