143586-27-0Relevant articles and documents
Design and synthesis of highly constrained factor Xa inhibitors: Amidine-Substituted bis(benzoyl)-[1,3]-diazepan-2-ones and bis(benzylidene)-bis(gem-dimethyl)cycloketones
Cui, Jian,Crich, David,Wink, Donald,Lam, Matthew,Rheingold, Arnold L.,Case, David A.,Fu, WenTao,Zhou, Yasheen,Rao, Mohan,Olson, Arthur J.,Johnson, Michael E.
, p. 3379 - 3392 (2007/10/03)
Two conformationally constrained templates have been designed to provide selective inhibitors of the coagulation cascade serine protease, Factor Xa (FXa). The most active inhibitor, 2,7-bis[(Z)-p-amidinobenzylidene)]-3,3,6,6-tetramethylcycloheptanone, exh
α-Oxosulfines: reactions with alkenes and alkynes
Still, Ian W. J.,Wilson, Donna Kaye T.
, p. 964 - 973 (2007/10/02)
Thiochroman-4-one 1,1-dioxide has been successfully converted into 3-sulfinylthiochroman-4-one 1,1-dioxide and the reactions of this α-oxosulfine with a series of alkenes have been carefully investigated.The α-oxosulfine was found to react as a Diels-Alde
